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Ivermectin, Mexico, Peru, India

Ivermectin and the odds of hospitalization due to COVID-19: evidence from a quasi-experimental analysis based on a public intervention in Mexico City

https://osf.io/preprints/socarxiv/r93g4/

Case study: Policy intervention in Mexico City

Increase in COVID-19 cases and with critical levels of hospital saturation during December 2020

Mexico City Government decided to expand population-based health
Interventions

Implementation of a prehospital home-care program

Combining early detection with antigen tests

230 kiosks

Phone-based follow up for positive patients

Since 28 December, 2020, medical ivermectin kits have been provided to positive mild to moderate symptomatic patients

Dyspnea, chest pain or cyanosis, referred to a hospital

Ivermectin, four 6mg tablets, two pills for two days

After one month, 83,000 medical kits delivered

Detailed data was collected on the evolution of patient illnesses

Quasi-experimental evaluation of the effects of the medical kits on
hospitalization

Kit receivers and non-kit receivers

Matched observations, adjusting by age, sex, COVID severity, and comorbidities

Controls, N = 156,468 patients with COVID-19 infection before implementing the ivermectin program

Experimental group, n = 77,381 after the implementation

Outcome variable: whether or not the person was hospitalized

Results

Negative and significant effect of the ivermectin-based medical kit on
the probability of hospitalization

Effect ranges from 50% to 76%

Difference in hospitalization odds between treated and untreated patients, statistically significant in all cases

As expected, the effect of the medical kits is higher and stronger among males, in older patients, and in cases without severe symptoms

Discussion and limitations

we found that the medical kit given en masse to patients who’d tested positive in Mexico City had a negative, significant, and robust effect on their odds of being hospitalized.

Independently of the medical telephone follow, level of hospital occupancy, specific period of time

Similar trend, Perú (Chamie-Quintero Et Al, 2021).

Principal mechanisms, reduction of viral load, in the patients that take ivermectin in early stages of the disease

Chamie-Quintero Et Al, 2021, Peru

https://osf.io/9egh4

25 states of Peru

Grouped by extent of IVM distributions

Maximal, medium, minimal

Reductions in excess deaths (30 days after peak deaths)

maximal, 74%
medium, 53%
minimal, 25%

Reduction of excess deaths is correlated with extent of IVM distribution by state p less than 0.002

This strongly suggests that IVM treatments can likewise effectively complement immunizations to help eradicate COVID-19.

The indicated biological mechanism of IVM,

competitive binding with SARS-CoV-2 spike protein,

is likely non-epitope specific,

possibly yielding full efficacy against emerging viral mutant strains.

Uttar Pradesh

https://indianexpress.com/article/cities/lucknow/uttar-pradesh-government-says-ivermectin-helped-to-keep-deaths-low-7311786/

Uttar Pradesh government, first to have introduced a large-scale “prophylactic and therapeutic” use of Ivermectin

Helped the state to maintain a lower fatality and positivity rate as compared to other states

Health Department introduced Ivermectin as prophylaxis for close contacts of Covid patients, August 6, 2020

Agra, Dr Anshul Pareek and State Surveillance Officer Vikssendu Agrawal

Administered Ivermectin to all RRT team members in Agra

None of them developed Covid-19

Despite being in daily contact

Despite being the state with the largest population base and a high population density, we have maintained a relatively low positivity rate and cases per million of population

Lower positivity and fatality rates may be attributed to the large-scale use of Ivermectin use UP

Written by Dr. John Campbell

Hello Everyone,My name is John Campbell and I am a retired Nurse Teacher and A and E nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally.

Comments

  1. IVM, HCQ are cheap vs the vax. Follow the money. The plan is about max vaccinations for some hidden agenda, not COVID. Why does the world care so much about the 1percent at risk of COVID vs half the world population dying of Cancer. BIG Pharma has no interest in finding a cure for the big C which is a billion dollar a year industry. Corporate for profit are only interested in making the big C a threatable chronic condition.

  2. i am, based on personal experience with many individuals, a huge advocate for using ivermectin and very much appreciate Dr. Campbell's report

  3. we have been using ivermectin for many years why why wont our gov. let us use it how much is drug cos. paying our politicians ???

  4. Greed is why we don’t hear about Ivermectin. They can’t make money with it so it’s worthless to them no matter how man people die. China should foot the bill for the whole world to get therapeutics or vaccines !

  5. Both Hyrochloroqine and Ivermectin are zinc ionophores, that is they facilitate the transport of Zn across cell membranes where it limits the virus' ability to replicate. Without giving patients zinc concurrently, neither drug is nearly as effective.

  6. The reason that Ivermectin+Hydroxychloroquine was vilified was simply that Trump said these medications worked, therefore these medicines was deemed ineffective. How many humans died simply because the LEFT WING MEDIA constantly lied and said the drugs did not work. Lawsuits should drive these despicable people into ruin.

  7. You kinda answered your own statement of vaccine people not recognizing therapeutics. It makes them seem at best ignorant at worst sinister. Especially considering this is a new vaccine and on top of that any side effects are getting suppressed. I am in health care and no longer trust public health..like zero. I’ll make my own decisions

  8. I am proud of you Dr. Campbell, as you seemed skeptical to alternatives before, but have been open to good statistics, and have come around to backing treatment that has efficacy.

  9. How can we organize for the near future when they start making arrests. They'll come to our homes and drag us out if we resist. The neighbors will think we have a meth lab in the basement and look the other way. We should be organized so that we all have speed dial that puts us in touch with thousands of people like us. An alarm goes off and the address of the one setting off the alarm appears. Then we all move quickly. Just a thought…we need to get the ball rolling

  10. Thanks Dr. Campbell from Japan, the home of Dr. Omura the founder of Ivermectin. Unfortunately, even the government over here has not recommended this potentially pandemic-ending drug as all governments seem to worship the US FDA. Please continue what you do to pressure those Aduhelm and Remdesivir approving €$#”!?&! at the FDA to recommend Ivermectin. Thank you!?

  11. Very curious as to why & how an anti-parasitic can destroy a 'virus' in vitro. I mean, do viruses or their protective outer shell contain the same structures that parasites do? How's it that a drug that disrupts the flow of electricity from one nerve cell to the next… has a side effect of disallowing a virus to multiply aka breed – Unless…. viruses and parasites are somehow genetically related…
    There's studies – remove the " "s and the one space ->
    "https://" pubmed.ncbi.nlm.nih.gov/32251768/
    "https://" pubmed.ncbi.nlm.nih.gov/33278625/

    This one published on June 15, 2021 even! Research has been seeing this med work the entire time… people just aren't being told about it, it's not considered 'approved' or 'acceptable' medicine
    "https://" pubmed.ncbi.nlm.nih.gov/34163159/

  12. The battle against this virus seems to be prolonged. Good video and had been following videos of Dr. John Campbell. Very informative. On a side note, I read that Zimbabwe is one of the early adopters on the use of ivermectin as early as February. If ivermectin is really effective and widely used in the country, how come the death toll and infection rates skyrocketed in June and July and these are the highest rates in the country (and still increasing exponentially)? What happened?

  13. If symptoms from adverse reactions to mRNA injections are diagnosed as Covid19 – will then this make it look like it has lower effect on the real virus infection? (Or may Ivermectin have positive effect even on these damages?)

  14. For a vaccine to be more acceptable for everyone the manufacture should be held liable if the person taking it get a side effect that makes that person health worse right?

  15. I eat garlic every day. An Indian guru on youtube claims too much garlic over-excites the nervous system. He may be correct; but I keep taking it. Also recently started adding Berberine which, among other things, supposedly has anti-parasitic properties. So far God willing I've been healthy while handling fiat cash and mixing among hundreds of folks daily throughout the "plannedemic".

  16. You're wondering why the deafening silence about Ivermectin, or why the WHO wont be looking into its efficacy? Follow the money: there's $100B in vaccines in jeopardy if a current drug costing US$/month per person will achieve similar results without compromising the body's immune system to fight these Covid19 variants. Then let's not forget the billions each quarter in booster shots which won't prevent anyone from getting reinfected by a new variant, or transmitting the virus.

  17. Is time to put high officials on the spot and pressure them to respond as its very irresponsible to remain quiet as people will die and corporate manslaughter looms on the horizon.

  18. Please can you have a 1-1 debate with Dr Sam Bailey about C-1.9. It would be interesting to see 2 doctors who have different views and opinions from one end of the spectrum to the other.

  19. Dr. Campbell "It is rediculous and indeed a Bit upsetting…" is a calm understatement !
    Let me say what Dr. Campbell can't.
    You MotherF!(£ers, who are blocking the use of Ivermectin, should be tried and convicted of conspiracy with Big Pharma, and those CEOs of BP should be Hung.

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